Drew University Immunology
Professor Barker · Drew University · 12 lectures with notes
Students in this class: ask your lecturer for the class code, and these lectures will already be in your library when you sign up.
Immunology Fall 2026: Lecture 13 B cell Development and Selection
B-cell development combines RAG-driven receptor diversity with central tolerance to remove or silence self-reactive cells before they leave bone marrow.
Immunology Fall 2026: Lecture 11 Generation of Antibody Diversity Part 2
Artemis hairpin opening and TdT nucleotide addition create junctional diversity during V(D)J recombination.
Immunology Fall 2026: Lecture 12 B cell Development
B-cell development uses staged V(D)J recombination and pre-B-cell receptor checks to produce cells with one functional heavy chain.
Immunology Fall 2026: Lecture 8 Antibody Structure and Function
Antibody variable regions recognize specific epitopes; constant-region Fc portions determine how antibodies recruit immune responses.
Immunology Fall 2026: Lecture 10 Generation of Antibody Diversity Part 1
V(D)J recombination and imprecise gene-segment joining let B cells generate antibody diversity far beyond the number of available genes.
Immunology Fall 2026: Lecture 9 Antibody Diversity
Antibody isotypes specialize immune protection, while VDJ recombination and junctional changes help generate up to 10^16 antibody specificities.
Immunology Fall 2026: Lecture 7 Cellular Innate Immunity Part 3/Antigens and Antibodies
NLR inflammasomes connect pathogen sensing to caspase-1-driven pyroptosis, while antibodies achieve specificity through distinct antigen epitopes.
Immunology Fall 2026: Lecture 6 Cellular Innate Immunity Part 2
PRR location and signaling route innate immunity toward bacterial inflammation or a type I interferon antiviral state.
Immunology Fall 2026: Lecture 4 Humoral Innate Immunity
Complement converts three distinct recognition routes into amplified microbial killing, inflammation, and opsonization.
Immunology Fall 2026: Lecture 5 Cellular Innate Immunity
Macrophages initiate inflammation through PRR signaling, while recruited neutrophils kill microbes and often die in the process.
Immunology Fall 2026: Lecture 2 Cells and Organs of the Immune System Part 1
Immune defenses combine barriers, fast broad innate responses, and slower specific adaptive responses built through clonal selection.
Immunology Fall 2026: Lecture 3 Cells and Organs of the Immune System Part 2
Immune cells develop in primary organs and meet pathogens in secondary sites organized by lymphatic drainage.